Peptide and oligonucleotide therapeutics offer exciting opportunities, but their unique ADME, bioanalytical and safety profiles can create complex preclinical development challenges. This webinar will explore how integrated DMPK, bioanalysis and toxicology strategies can help teams better understand ADME properties, select fit-for-purpose measurement approaches, and translate preclinical findings into IND-enabling decisions. Attendees will gain practical insight into how cross-functional alignment can support more efficient and confident development of these emerging modalities.
This webinar focuses on the three common ADME-PK challenges of peptide and oligo drugs—stability, permeability, and distribution—and presents ADME-PK solutions through case studies from the perspectives of biotransformation, permeability, and in vivo distribution at preclinical stage.
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