Why Choose WuXi AppTec DMPK?

Fast and Reliable Data Delivery
High-Throughput Automation Platforms
Experienced and Professional Teams
High Standard Instruments and Facilities
Integrated Service

Fast and Reliable Data Delivery

Fast Data Delivery

No lead time for in vitro and in vivo assays
Less than five working days for screening assays
TAT 4 months for regular IND-enabling package
Reliable Experimental Results

Meet IND and NDA requirements of FDA, NMPA and EMA
Successfully pass over 15 years of audits

Digital operation and management platform

Precise and intelligent operation system, efficient and safe data delivery

Project Management System

Compound Management System

Electronic Lab Notebook System

Report Automation System

QuickTracer Tracking System

- Precise and intelligent process management
  Systematic management from contract signing to project delivery makes the process more transparent and more intelligent.
- Automated and efficient experiment management
  Automatically creates millions of sample labels every year and scans codes to capture the dynamic trajectory of samples.
- Safe and compliant authority management
  The system has a clear layered structure with authority limitations, so all users operate only within the scope of their authorization.
- Compound Storage Services
  With a storage throughput of over one million compounds and a historical management record of more than one million compounds, the management platform integrates automated storage equipment with compound management systems to provide clients with safe, accurate, and efficient compound management services.
- 100% Recording Accuracy of Compounds
  The compounds are weighed on a high-precision balance with real-time transmission and recording of weighing data. Tens of thousands of weighing times occur per month, but scientists can accurately retrieve the inventory and usage of compounds.
- 100% Accuracy of Aliquot and Solution Preparation
  The Hamilton automatic workstation calculates the required amount of solvent according to the instructions and automatically prepares the solution with a target concentration and aliquot. Real-time data synchronization guarantees that the process is more reliable.
- Real-time Recording of Operating Traces
  An audit trail system can record all online operation traces from users in real-time, ensuring accurate and safe records.
- Standard Recording Template
  The customized recording system was developed to precisely match DMPK experimental types and achieve online recording. The sample code can be acquired with one click instead of manual editing, having accurately generated sample codes for over 150,000 cumulative projects.
- Secure Data Backup
  VERITAS NetBackup software enables incremental backup of electronic data daily and full weekly backup, so data is secured and recoverable.
- Comprehensive Coverage of Assay Types
  Various automated programs aid in the efficient writing of reports, thereby accelerating the assay process.
- Reduction of Human Writing Errors
  To reduce human errors, copying and pasting was eliminated from copy and paste steps which occurred in traditional editing.
- Man-machine Collaboration to Ensure Quality
  The human-computer synergy mode not only improves writing efficiency by 50%, but also allows scientists to shift their focus of work from data alignment to data plausibility, which doubles the accuracy of data and reports.
- Tracking System
  Display project progress in total transparency and real-time with one click on your PC or mobile phone.

High-Throughput Automation Platforms

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To deliver high-throughput and fast testing services, WuXi AppTec DMPK continues to leverage the potential of automation. We have successfully validated and deployed several high-throughput automation platforms, including in vitro ADME high-throughput integrated automated workstation, biological sample pre-treatment full-automation system, smart compound library, automated blood sampler and plasma separation systems, intelligent animal facility and scheduling system, etc. to reduce the human error, improve data quality, and shorten the turnaround time, thus accelerating clients' development process.

Experienced and Professional Teams

18+
Years of experience
1,000+
Employees
1,600+
Global clients
1,500+
Successful IND filings supported
200+
Assay types
300,000+
In vitro experiments conducted per year
20,000+
In vivo experiments conducted per year
180,000+
Samples analyzed per week

View More About Our Teams

Comprehensive Services with Streamlined Communications

We have a specialized and dedicated service model. Each client will be connected to a dedicated study director who will provide comprehensive management services for the pharmacokinetic project from drug discovery to the clinical phase. Our Study Director, with a professional background in pharmacokinetic research and extensive drug development experience, collaborates with senior DMPK experts and functional heads to provide comprehensive project management and technical support. This ensures the high-quality and efficient project delivery.
Innovation and Development

Our team of scientists continues to strive to improve our research capabilities and broaden our scope of drug-enabling platforms through innovative ideation and partnership. We have established pharmacokinetic research strategies and test service systems for each type of featured drug modality（such as therapeutic proteins, peptides, oligonucleotides, antibody-drug conjugates (ADC), proteolysis-targeting chimeras (PROTACs*), etc.).
The findings and results were reported in scientific articles in peer-reviewed journals, international academic conferences, and patent applications.

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High Standard Instruments and Facilities

We provide comprehensive pharmacokinetic services from early screening, and preclinical development, to clinical research through high-standard instruments and facilities including industry-leading Liquid Chromatography-Mass Spectrometry (LC-MS), Ligand Binding Assay (LBA) platforms, high-resolution mass spectrometry (HRMS), data processing software, radioactivity detectors, etc. Our animal facilities are fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC International).

Non-GLP BA
MetID
Radiolabeled ADME
High Standards of Animal Facilities

Non-GLP BA

Leveraging liquid chromatography-mass spectrometry (LC-MS), ligand binding assay (LBA), and automated instruments, we offer high-throughput and efficient qualitative and quantitative bioanalysis services. This supports the research of candidate drugs, metabolites, biomarkers, and large molecules in in vivo and in vitro samples from screening to the IND filing stage.
- Mass Spectrometer
- Ligand Binding
- Nucleic Acid Detection qPCR
- Full automation, High-throughput
- - Waters Vion™ QTof
  - Orbitrap Eclipse™ Tribrid™
  - Sciex Triple Quad™ 7500+
  - PE NexION 2000
- - MESO Sector S 600MM
  - BD LSRFortessa™ X-20
  - Molecular Devices SpectraMax M5e
- - QIAcube HT
  - QuantStudio™ 7 Flex Real-Time PCR System
  - QIAgility
- - Apricot Designs Dual Arm
  - High-throughput intelligent delivery system
MetID

The team is equipped with industry-leading high-resolution mass spectrometry platforms, such as Thermo Scientific™ Orbitrap Eclipse™ Tribrid™ and Waters®VionTM IMS QTof. In addition, professional data processing softwares are available within the team, including Thermo Scientific™ Compound Discoverer™/Thermo Scientific™ BioPharma Finder™, UNIFI®, and Mass-MetaSite (Molecular Discovery).
- High-Resolution Mass Spectrometry
- Equipment for Radioactivity Detection
- - Orbitrap Eclipse™ Tribrid™
  - Orbitrap Exploris™ 480
  - Q-Exactive™ HF
  - VION™ IMS QTof
  - Q-Exactive™ Plus
  - Q-Exactive™
  - LTQ Orbitrap XL
  - Xevo®G2 QTof
- - Solid scintillation counter: off-line detection of radioactivity
  - Liquid scintillation counter: total radioactivity detection
  - On-line detection of radioactivity
Radiolabeled ADME

Utilizing radiolabeled compound synthesis techniques and radioactive detection equipment, we offer pharmacokinetic studies of test drugs marked with radioactive isotopes.
- Radiolabeled ADME
- - Q-Exactive™ HF
  - Orbitrap Exploris™ 480
  - Thermo LTQ-Orbitrap
  - SCIEX API 6500
  - Liquid Scintillation Counter
  - β-RAM Online Radioactivity Detectorβ-counter
  - Solid Scintillation Counter
  - Cryostat Microtome
  - Multifunctional Laser Imager
  - Liquid Scintillation Counter
  - Triple Quad MS
  - 1H NMR
High Standards of Animal Facilities

The Animal facilities of WuXi AppTec DMPK are in Shanghai, Suzhou, Nantong, and Nanjing, respectively. All facilities are fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC International). Animal barrier facilities in Shanghai, Suzhou, and Nantong have obtained the OLAW-approved Animal Welfare Assurance.
- Animal Facilities

Integrated Service

Comprehensive Support to Accelerate New Drug R&D Process

WuXi AppTec DMPK works closely with other departments at WuXi AppTec to offer a one-stop service to clients.

As a global company with operations across Asia, Europe, and North America, WuXi AppTec provides a broad portfolio of R&D and manufacturing services that enable the global pharmaceutical and life sciences industry to advance discoveries and deliver groundbreaking treatments to patients. Through its unique business models, WuXi AppTec’s integrated, end-to-end services include chemistry drug CRDMO (Contract Research, Development and Manufacturing Organization), biology discovery, preclinical testing and clinical research services, advanced therapies CTDMO (Contract Testing, Development and Manufacturing Organization), helping customers improve the productivity of advancing healthcare products through cost-effective and efficient solutions.

Our Vision

"Every drug can be made and every disease can be treated” through building the open-access platform with the most comprehensive capabilities and technologies in the global healthcare industry."

Integrated, End to end enabling Platform

6,000+
Innovative customers enabled
30+
Customers from more than 30 countries

Chemistry Platform (WuXi Chemistry)
Biology Discovery Platform (WuXi Biology)
Testing Services Platform (WuXi Testing)
Advanced Therapies CTDMO Platform (WuXi ATU)

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