The DMPK Service Department is one of the business units under the Laboratory Testing Division. It is primarily responsible for in vivo and in vitro pharmacokinetics studies. When you partner with WuXi AppTec for drug discovery and development services, you gain access to an integrated worldwide network of facilities that offer a full range of discovery screening, preclinical development, clinical drug metabolism, and pharmacokinetic (DMPK) platforms and services. These include in vitro absorption, distribution, metabolism, and excretion (ADME) studies and in vivo pharmacokinetic studies, metabolite identification studies, quantitative autoradiography studies, human radioactive substance balance, and metabolite safety evaluation studies. With locations in the United States (New Jersey) and China (Shanghai, Suzhou, Nanjing, and Nantong), we can help you navigate every aspect of the drug development process—no matter what the stage.
The DMPK Service Department has a diversified client community, covering more than 90% of the world’s large pharmaceutical companies with more than 1,000 small and medium-sized biopharmaceutical companies, virtual companies, non-profit organizations, and academic institutions. As a global DMPK service provider, we are committed to delivering all clients with high-quality data, precise R&D strategies, and excellent services to meet the unique needs of every client and become the preferred partner for DMPK studies.
High-throughput screening of DMPK experiments suitable for early R&D stages
Experimental design and research strategy according to the characteristics of the project.
Pharmacokinetics study strategies and optimization recommendations based on the characteristics of test compounds
Comprehensive interpretation of pharmacokinetics properties of test compounds
Species selection to support GLP toxicological assessment on safety
Support for PK/PD studies
IND submission strategy and IND study packages (Support clients in submitting IND applications to regulatory agencies worldwide)
A basis for dosing frequency and dose setting
Improved package inserts of drugs
·Precise and efficient digital operation management systems ensure hundreds of thousands of in vitroand in vivo experiments annually.
·Digitalization of the whole process from test article receiving to report submission protects client intellectual property.
·The project progress is transparent and visible. Clients can remotely review project progress in real-time.
·To prospectively establish a research and testing service system for cutting-edge pharmaceutical R&D areas and new drug modalities.
· We successfully support IND applications in multiple innovative fields to ensure client success.
·Papers on DMPK studies submitted by our scientists are regularly published in notable international journals.
In Vitro ADME Studies, In VivoPharmacokinetics Studies, Drug Metabolite Identification Studies, Pharmacokinetics Studies of Radiolabeled Test Articles, Non-GLP Bioanalysi
In Vitro ADME Studies, Rodent Pharmacokinetics Studies, Drug Metabolite Identification Studies, Non-GLP Bioanalys
In Vitro ADME Studies, in VivoPharmacokinetics Studies, Drug Metabolite Identification Studies, pharmacokinetics Studies of Radiolabeled Test Articles, Non-GLP Bioanalysis
In Vivo Pharmacokinetics Study, Non-GLP Bioanalysis
in Vivo Pharmacokinetics Study, Non-GLP Bioanlaysis