Determination of DS-8201 in Rat Plasma Using mSPE Magnetic Beads Method in Couple with Liquid Chromatography-Tandem Mass Spectrometry

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February 10,2026

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Magnetic SPE (mSPE) beads are composed of magnetic cores coated with polymer adsorbent materials, such as HLB and MCX. By capturing and enriching trace amounts of target analytes in the sample matrix, these beads can overcome the shortcomings of clogging and complicated operation associated with traditional solid-phase extraction cartridges. They make the separation and concentration process simple, fast, and efficient. Compared with traditional SPE, mSPE increases efficiency by more than 30% and reduces costs by over 90%.

Determination-of-DS-8201-in-Rat-Plasma-Using-mSPE-Magnetic-Beads-Method-in-Couple-with-Liquid-Chromatography-Tandem-Mass-Spectrometry.jpg

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