DMPK Strategies for Proteolysis-Targeting Chimeras: Addressing ADME and PK Challenges

Webinars

Webinars Overview

This program provides practical guidance for selecting optimal in vitro systems to evaluate PROTAC-specific ADME properties, covering advanced assays for solubility, permeability, protein binding, and biotransformation pathway elucidation, and further examines solutions to enhance PROTAC bioavailability through innovative formulation approaches, supported by case studies. Participants will gain expertise in designing and interpreting in vivo PK studies. The program also covers bioanalytical approaches and advanced techniques for PROTAC quantification.

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