X-ray/CT Dynamic Tracking Technology: A Visualized Solution for In Vivo Behavior of Oral Peptide Drugs— Supporting Formulation Development and Large Animal PK Studies

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July 17,2026

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This study established a novel tracer technology based on image assistance: oral preparations were made by mixing peptide drugs with medical barium sulfate in a certain proportion. With the help of two-dimensional real-time dynamic imaging of X-rays and three-dimensional high-resolution tomography of CT, the real-time position, movement trajectory and disintegration and dispersion process of barium sulfate were tracked, and the spatiotemporal distribution characteristics of the drug in each segment such as the stomach, duodenum, jejunum, ileum and colon were indirectly inferred.

X-rayCT Dynamic Tracking Technology A Visualized Solution for In Vivo Behavior of Oral Peptide Drugs— Supporting Formulation Development and Large Animal PK Studies.jpg

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