DMPK Strategies for Advancing Preclinical Development of AOC Therapeutics

Webinars

Webinars Overview

The presentation outlines a holistic DMPK strategy for AOC development. Specifically, it details the critical ADME investigations required for the intact conjugate, linker, and oligonucleotide payload. A significant focus is placed on addressing key challenges in AOC DMPK studies, including the selection of appropriate analytical platforms for preclinical PK assessments and the characterization of biotransformation. These points are illustrated and reinforced through relevant case studies.

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