Vehicle Screening and Optimization to Improve Oral Bioavailability of PROTAC Drugs

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July 17,2026

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Throughout preclinical formulation development of PROTACs and similar poorly soluble drugs, it is crucial to improve the solubilizing capacity of vehicles and effectively maintain supersaturation. This can effectively support the exposure assessment of these drugs in preclinical in vivo studies.

Vehicle Screening and Optimization to Improve Oral Bioavailability of PROTAC Drugs.jpg

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