Establishment of in Vitro Human Hepatocytes Method to Access CYP Inhibition Potential

Posters
July 17,2026

Posters Overview

Cytochrome P450 (CYP) inhibition studies are routinely conducted in human liver microsomes (HLM). However, microsomal systems may overexpose CYP enzymes to test articles, especially high-molecular-weight drug candidates, due to limited membrane permeability, potentially increasing the risk of overestimating CYP inhibition. Therefore, an in vitro assay using human hepatocytes was established to provide more physiologically relevant conditions for CYP inhibition assessment.

Establishment of in Vitro Human Hepatocytes Method to Access CYP Inhibition Potential.jpg

Complete the form to view and download this poster.

First name *

* Please check the filled content
Last name *

* Please check the filled content
Email address *

* Please check the filled content
Phone number
Company *

* Please enter a valid e-mail address
Department *

* Please check the filled content
Country/District *

* Please check the filled content
Position *

* Please check the filled content
City *

* Please check the filled content
Focus area (Service you are interested in)

I want to receive the latest news, insights, and communication from WuXi AppTec DMPK. I understand that I can unsubscribe at any time.

I acknowledge and agree that WuXi AppTec DMPK may transfer my personal information across borders for the purpose of providing products and services through resources worldwide.

By clicking submit below, you consent to WuXi AppTec DMPK collecting and processing the information you provide for our internal purposes, in accordance with our privacy policy.

* Please agree to the Privacy Policy
Submit

Stay Connected

Keep up with the latest news and insights.

Email address*

* Please check the filled content
First name*

* Please check the filled content
Last name*

* Please check the filled content
Company*

* Please check the filled content

By clicking submit, you consent to WuXi AppTec DMPK collecting and processing the information you provide for our internal purposes, in accordance with our privacy policy.

* Please agree to the Privacy Policy

Submit