A High-Sensitivity Stem-Loop RT-qPCR Method for RISC-Loaded siRNA Quantitation

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March 26,2026

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This study aims to establish and validate a highly selective and ultrasensitive bioanalytical method for quantifying RISC-loaded siRNA in target tissues. This approach will enable a more accurate assessment of drug PK/PD profiles and provide a scientific basis for dose optimization of siRNA therapeutics.

A High-Sensitivity Stem-Loop RT-qPCR Method for RISC-Loaded siRNA Quantitation

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