WuXi Science Forum is coming to Copenhagen and Basel! Join us on September 9 and 11 for the dynamic, full-day event designed to accelerate innovation through thought leadership, collaboration, and scientific excellence.
Speakers
Li Qu, Ph.D. | Director I, WuXi LTD-DMPK, WuXi AppTec
Dr. Li Qu graduated from Fudan University and joined WuXi AppTec in 2021. She’s responsible for supporting in vitro and in vivo pharmacokinetic studies of new modalities. She has established multiple bioanalytical platforms based on Ultra-performance Convergence Chromatography (UPC²) and High-Resolution Mass Spectrometry (HRMS), accumulating extensive experience in the fields of chiral drugs, fusion protein, albumin-delivered drug, and antibody-drug conjugates (ADCs).
Presentation topic title:Advanced Bioanalytical Strategies and Analytical Innovation for ADC Therapeutics
Jing Jin, Ph.D. | Senior Director, WuXi LTD-DMPK, WuXi AppTec
Dr. Jing Jin currently serves as the Senior Director, heading the DMPK Study Director team at WuXi AppTec. Before joining WuXi AppTec in 2016, he worked as an Investigator of Clinical Pharmacology at Novartis. Over these roles, he has gained extensive experience in DMPK research of multiple drug modalities, including oligonucleotides, protein degraders, and antibody-drug conjugates. Dr. Jing Jin received his Ph.D. in Pharmacology from Vanderbilt University in Nashville, TN, and completed his undergraduate training in Biochemistry at Nanjing University, China.
Presentation topic title:Navigating Complexities in Oligonucleotides: DMPK Strategies and CNS Targeting Solutions
Agenda
2025 Science Forum —— Copenhagen
• Date: Tuesday, September 9, 2025
• Time: 08:00-14:40 (CEST)
2025 Science Forum —— Basel
• Date: Thursday, September 11, 2025
• Time: 08:00-15:05 (CEST)
Our posters
Other Resources
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Our posters
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Other Resources
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Bioanalytical Strategy for Antibody-Drug Conjugates (ADCs) Based on an Integrated Mass Spectrometry Bioanalytical Platform
In this study, we summarised a comprehensive bioanalytical strategy of ADCs based on mass spectrometry platforms, including tandem mass spectrometry (MS/MS) and high-resolution mass spectrometry (HRMS). Including measurement for total antibody, conjugated antibody, free payload, conjugated payload, total payload, drug-to-antibody ratio (DAR), and biotransformation. A deep understanding of these contents is key to characterising ADC behaviour through drug discovery to development stages.
Impact of Bovine Serum Albumin on In Vitro Permeability and ABC Transporter Mediated Drug Interaction EvaluationThe Determinants in Evaluating siRNA Plasma Protein Binding Using Agarose Gel Electrophoretic Mobility Shift Assay (EMSA)Does the Flux Competition Method Add Significant Value in Species Difference Protein Binding Evaluation?Effects of Lipoprotein Binding and Plasma Dilution on the Accuracy of Ultracentrifugation Method in Plasma Protein BindingEffects of Anesthesia and Different Lymphatic Fluid Collection Methods on the Lymphatic Transport of Orally Administered Drugs: A Comparative Study in RatsCharacterization of 14 Pharmaceutical Excipients in the Caco-2 Permeability AssayPlasma Protein Binding of Oligonucleotides Using Rapid Agarose Gel Electrophoretic Mobility Shift AssayStrategies for Enhancing Oral Exposure of Water-Insoluble CompoundsPlasma Protein Binding of Nine Antisense Oligonucleotides by UltrafiltrationEstablishment of the Flux Dialysis Method for Highly Bound Compounds in Human Plasma and Rat Brain HomogenateDAR Distribution Determination for Antibody-drug-conjugates (ADCs) by LC-HRMS in In Vitro and In Vivo StudiesView More -
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Evaluating Oral Peptides' Gastrointestinal Absorption: Methods and Applications
ArticlesAug 28,2025 -
Advancing Novel Therapeutics with Innovative DMPK Strategies in Metabolism and Bioanalysis
WebinarsAug 22,2025 -
An Efficient and Environmental Friendly Method for the Determination of Nucleoside Phosphate Compounds by Using LC-MS/MS
PostersAug 01,2025
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