Advancements in drug design have resulted in resurging interest in drugs that form covalent bonds with their targets, often referred to as targeted covalent inhibitors. Covalent drugs have the potential to provide enhanced potency and prolonged duration of action compared to non-covalent drugs. However, it is critical for covalent inhibitors to exhibit sufficient selectivity to mitigate off-target effects caused by binding to unintended proteins.
In this webinar, our speaker will introduce the unique DMPK properties of covalent drugs to support lead optimization efforts.
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Dr. Qigan Cheng
Dr. Qigan Cheng obtained his PhD from University of South Florida. After graduation, he worked in the field of medicinal chemistry and process chemistry. He then joined in WuXi AppTec as DMPK study director in 2019. Till now he has supported more than 20 IND-enabling projects successfully.
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