Effects of Anesthesia and Different Lymphatic Fluid Collection Methods on the Lymphatic Transport of Orally Administered Drugs: A Comparative Study in Rats
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Posters
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October 30,2024
Posters Overview
With the continuous progress of new drug development technology, the proportion of lipophilic drug candidates among new chemical entities is increasing. These compounds exhibit poor water solubility, which affects the oral bioavailability of drugs. The absorption of oral dosage forms in the body primarily involves intestinal vascular and intestinal lymphatic absorption into the bloodstream. The investigation of drug absorption, distribution, and transportation through the lymphatic circulation has gained significant attention in the mechanistic study of bioavailability.
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