Determination of a Cucurbit[7]uril (CB[7])–PEG Conjugate in Dog Plasma and Rat Plasma by LC-MS/MS

Posters
July 10,2024

Posters Overview

Cucurbit[7]uril (CB[7])–PEG conjugate is comprised of polyethylene glycol (PEG) and a discrete macrocyclic host (CB[7]) (marketing available) with a cavity that is selective for complementary binding to certain guest ligands, offers several advantages, including improved drug solubilization, prolonged circulation, reduced immunogenicity, increase stability, controlled release and enhanced safety. To avoid potential tissue toxicity caused by high accumulation of PEGs after long-term administration, full understanding of the related pharmacokinetic behavior of the conjugate is significant in evaluating of the overall safety.

75Determination of a Cucurbit[7]uril.jpg

Complete the form to view and download this poster.

First name *

* Please check the filled content
Last name *

* Please check the filled content
Email address *

* Please check the filled content
Phone number
Company *

* Please enter a valid e-mail address
Department *

* Please check the filled content
Country *

* Please check the filled content
Position *

* Please check the filled content
City *

* Please check the filled content
Focus area (Service you are interested in)
I want to receive the latest news, insights, and communication from WuXi AppTec DMPK. I understand that I can unsubscribe at any time.

I acknowledge and agree that WuXi AppTec DMPK may transfer my personal information across borders for the purpose of providing products and services through resources worldwide.

By clicking submit below, you consent to WuXi AppTec DMPK collecting and processing the information you provide for our internal purposes, in accordance with our privacy policy.

* Please agree to the Privacy Policy
Submit

Stay Connected

Keep up with the latest news and insights.

Email address*

* Please check the filled content
First name*

* Please check the filled content
Last name*

* Please check the filled content
Company*

* Please check the filled content

By clicking submit, you consent to WuXi AppTec DMPK collecting and processing the information you provide for our internal purposes, in accordance with our privacy policy.

* Please agree to the Privacy Policy

Submit