Evaluation of the Safety and Cross-Species Tolerability of Solutol HS 15 via Intravenous Administration in Various Animals

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August 08,2025

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This study aimed to explore concentration-dependent safety limits and evaluate the risk of combined solvent use via intravenous administration of Solutol HS 15 in Beagle dogs. Additionally, we assessed tolerability differences across species, including mini-pigs, cynomolgus monkeys, and Dutch belted rabbits, to inform species-appropriate formulation design.

Evaluation of the Safety and Cross-Species Tolerability of Solutol HS 15 via Intravenous Administration in Various Animals

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