Nervous System Drug Nervous System Drug Delivery Techniques in Large Animals (Non-Rodents): Enhancing DMPK Research for Oligonucleotide DrugsDelivery Techniques in Large Animals (Non-Rodents): Enhancing DMPK Research for Oligonucleotide Drugs

Posters
April 29,2025

Posters Overview

The intrathecal administration technique provides an effective delivery route for oligonucleotide drugs, overcoming of biological barriers and enhancing therapeutic efficacy, particularly in the treatment of central nervous system (CNS) diseases. In non-human primates, conventional intrathecal (IT) administration is typically performed via lumbar puncture, which suffers from a low success rate and inconsistent data. This inconsistency poses challenges for the development of new CNS drugs. In contrast, utilizing a lumbar catheter allows for a 100% success rate in drug administration as well as the potential for multiple repeated doses.

Array

Complete the form to view and download this poster.

First name *

* Please check the filled content
Last name *

* Please check the filled content
Email address *

* Please check the filled content
Phone number
Company *

* Please enter a valid e-mail address
Department *

* Please check the filled content
Country *

* Please check the filled content
Position *

* Please check the filled content
City *

* Please check the filled content
Focus area (Service you are interested in)
I want to receive the latest news, insights, and communication from WuXi AppTec DMPK. I understand that I can unsubscribe at any time.

I acknowledge and agree that WuXi AppTec DMPK may transfer my personal information across borders for the purpose of providing products and services through resources worldwide.

By clicking submit below, you consent to WuXi AppTec DMPK collecting and processing the information you provide for our internal purposes, in accordance with our privacy policy.

* Please agree to the Privacy Policy
Submit

Stay Connected

Keep up with the latest news and insights.

Email address*

* Please check the filled content
First name*

* Please check the filled content
Last name*

* Please check the filled content
Company*

* Please check the filled content

By clicking submit, you consent to WuXi AppTec DMPK collecting and processing the information you provide for our internal purposes, in accordance with our privacy policy.

* Please agree to the Privacy Policy

Submit