Advancements in Exposed Polar Surface Area (EPSA) for Predicting Permeability in Early Drug Discovery

Posters
April 29,2025

Posters Overview

This poster discusses the development of EPSA, reviews its applications as a predictive tool for passive membrane permeability, and highlights its significance in designing drugs with high oral bioavailability. We further optimized the chromatographic conditions (reducing single-needle detection time to 6.5 minutes) to measure EPSA, present data for a range of bRo5 and Ro5 compounds, and offer alternative high-throughput and high-quality detection methods for drug screening in the drug discovery stage.

Array

Complete the form to view and download this poster.

First name *

* Please check the filled content
Last name *

* Please check the filled content
Email address *

* Please check the filled content
Phone number
Company *

* Please enter a valid e-mail address
Department *

* Please check the filled content
Country *

* Please check the filled content
Position *

* Please check the filled content
City *

* Please check the filled content
Focus area (Service you are interested in)
I want to receive the latest news, insights, and communication from WuXi AppTec DMPK. I understand that I can unsubscribe at any time.

I acknowledge and agree that WuXi AppTec DMPK may transfer my personal information across borders for the purpose of providing products and services through resources worldwide.

By clicking submit below, you consent to WuXi AppTec DMPK collecting and processing the information you provide for our internal purposes, in accordance with our privacy policy.

* Please agree to the Privacy Policy
Submit

Stay Connected

Keep up with the latest news and insights.

Email address*

* Please check the filled content
First name*

* Please check the filled content
Last name*

* Please check the filled content
Company*

* Please check the filled content

By clicking submit, you consent to WuXi AppTec DMPK collecting and processing the information you provide for our internal purposes, in accordance with our privacy policy.

* Please agree to the Privacy Policy

Submit