A Sensitive and Efficient LC-MS/MS Method for Creatinine-d5 Analysis in In Vitro OCT2 Inhibition Assay

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November 28,2024

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To accurately evaluate the inhibitory activity of in vitro OCT2 transporter, creatinine-d₅ was used instead of creatinine. This approach eliminates the interference caused by endogenous creatinine and enables the establishment of a novel and efficient LC-MS/MS method.

A Sensitive and Efficient LC-MSMS Method for Creatinine-d5 Analysis in In Vitro OCT2 Inhibition Assay.png

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