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Bioanalytical Instrument Platform

Through the advanced liquid chromatography-mass spectrometry (LC-MS), ligand binding assay (LBA), and nucleotide analysis platforms, we provide fully automated, high-throughput, efficient and comprehensive quantitative bioanalysis services. This supports the research, screening, and optimization of drug candidates, metabolites, biomarkers, and large molecule immunogenicity.

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  • Overview

  • Strengths

  • Instrument Platforms

  • FAQs

  • Related Resources

  • Related Services

DMPK BA

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Overview

Our team has established a variety of advanced LC-MS platforms to meet customers' analytical needs at different stages. We have a wide range of mass spectrometers, such as multiple generations of Sciex triple quadrupole mass spectrometers, PerkinElmer NexION 2000 ICP-MS, Waters XeVo G2 QToF, Vion QToF, and ThermoFisher Orbitrap Q-Exactive™ Plus, Q-Exactive™ HF, and Eclipse systems. These mass spectrometry systems are coupled with ultrahigh-performance liquid chromatography systems such as Waters UPLC and Shimadzu UHPLC. For the screening stage in vitro sample bioanalysis, high throughput autosamplers such as CTC and ADDA are utilized. Molecular Devices SpectraMax M5/M5e microplate readers, Meso Scale Discovery SECTOR S 600 (which is capable for 384-well format assay) and QuickPlex SQ120, and BD LSRFortessa™ cell analyzer are applied for the LBA analysis of large molecules and cells. In addition, we have multiple automated sample preparation systems, such as the HP D300e instruments, Hamilton Microlab STAR™ and STARLET™ liquid handler workstations, and Night Watcher Full Automation System, to support fast sample preparation.

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Strengths

  • 10 +

    Types of bioanalysis platforms

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  • 200+

    Analytical instruments

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  • 24 h

    Fully automated sample preparation

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Instrument Platforms

  • Mass Spectrometer

  • Ligand Binding

  • Nucleic Acid Detection qPCR

  • Full Automation, High-throughput

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      Waters Vion™ QTof

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      Orbitrap Eclipse™ Tribrid™

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      Sciex Triple Quad™ 7500

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      PE NexION 2000

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      MESO Sector S 600MM

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      Molecular Devices SpectraMax M5e

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      BD LSRFortessa™ X-20

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      QIAcube HT

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      QuantStudio™ 7 Flex Real-Time PCR System

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      QIAgility

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      Apricot Designs Dual Arm

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      High-throughput intelligent delivery system

FAQs

  • How often is preventive maintenance (PM) performed on laboratory equipment?

    PM is typically carried out annually, but the specific frequency may vary depending on the type of equipment, frequency of use, and manufacturer's recommendations. In high-usage lab environments, certain equipment, such as mass spectrometers, may require PM every six months or quarterly.

  • Can you customize instrument analysis platforms for specific applications?

    Yes, we can. We have a variety of types of mass spectrometers, ultra-high-performance liquid chromatography systems, high-throughput auto-samplers, and automated sample preparation systems. The diversity of these devices and technologies allows us to customize solutions based on specific customer needs, whether for bioanalysis of small and large molecules in various in vivo and in vitro biological matrices. This personalized service ensures that our analysis results are highly accurate and efficient, meeting customers' needs at different stages.

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