Preclinical Drug Development Testing for Peptide

Peptides – a unique class of pharmaceutical compounds composed of a series of well-ordered amino acids have become a popular area of drug development. However, due to their structures and properties, peptides pose many challenges to peptide drug development. WuXi AppTec's Drug Metabolism and Pharmacokinetics (DMPK) Service Department has built a well-established druggability evaluation system for peptides based on the team's experience in peptide research. The system provides a complete solution for DMPK studies of peptides, covering stability and metabolic soft spot research at the screening stage, evaluation of in vivo pharmacokinetics and species selection at the preclinical candidate tage, and radiolabeled ADME experiments at the IND application and clinical trial stage.