Factsheet-Intrathecal Administration in Rats and Monkeys

Brochures
August 08,2025

Brochures Overview

WuXi AppTec DMPK developed an optimized intrathecal catheterization technique for rats and monkeys, enabling precise CNS-targeted drug delivery (bolus/infusion). Achieved 100% success (60 rats, 80 monkeys), high catheter patency (>30d rats; >90d NHPs), minimal invasiveness, and serial CSF/blood sampling. Validated with Nusinersen, showing low data variability and reliable exposure, accelerating preclinical CNS drug R&D.

Factsheet-Intrathecal-Administration-in-Rats-and-Monkeys.jpg

Complete the form to view and download this brochure.

First name *

* Please check the filled content
Last name *

* Please check the filled content
Email address *

* Please check the filled content
Phone number
Company *

* Please enter a valid e-mail address
Department *

* Please check the filled content
Country *

* Please check the filled content
Position *

* Please check the filled content
City *

* Please check the filled content
Focus area (Service you are interested in)
I want to receive the latest news, insights, and communication from WuXi AppTec DMPK. I understand that I can unsubscribe at any time.

I acknowledge and agree that WuXi AppTec DMPK may transfer my personal information across borders for the purpose of providing products and services through resources worldwide.

By clicking submit below, you consent to WuXi AppTec DMPK collecting and processing the information you provide for our internal purposes, in accordance with our privacy policy.

* Please agree to the Privacy Policy
Submit

Stay Connected

Keep up with the latest news and insights.

Email address*

* Please check the filled content
First name*

* Please check the filled content
Last name*

* Please check the filled content
Company*

* Please check the filled content

By clicking submit, you consent to WuXi AppTec DMPK collecting and processing the information you provide for our internal purposes, in accordance with our privacy policy.

* Please agree to the Privacy Policy

Submit