Large Animal (Non-Rodent) PK Study Part Ⅲ List of Organ and Tissue Collection

Tissue distribution research is a critical component of preclinical pharmacokinetics studies. It reveals the distribution pattern of drugs among various tissues and organs in the body, playing a crucial role in understanding the mechanism of drug action, predicting drug efficacy and toxicity, and optimizing drug administration regimens. In this process, the importance of tissue dissection and separation is self-evident. It allows for the precise acquisition of drug concentrations in specific tissues or organs, providing direct and accurate data support for the distribution pattern of drugs within the body. This, in turn, enables a more accurate assessment of drug safety and efficacy, providing essential evidence for subsequent clinical trials and drug development.