Permeability & Transporter Services Part Ⅱ: ABC Transporters

Brochures
June 06,2024

Brochures Overview

ABC transporters actively transport endogenous and exogenous substrates through biological membrances in body tissues by coupling ATP binding, hydrolysis, and phosphate release, so they play a critical role in drug disposition by affecting absorption, distribution, and excretion. As reported in numerous publications, ABC transporters influenced the pharmacokinetics characteristics of many drugs as well as the related transporter-mediated drug interactions.

61Permeability & Transporter Services Part ⅡABC Transporters.jpg

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