2023-05-04 17:24:22

DMPK Optimization of Proteolysis-Targeting Chimeras (PROTAC)

Webinar Overview

Proteolysis-targeting chimeras (PROTACs) are bifunctional molecules that leverage the body's internal protein disposal system to target and degrade disease-causing proteins. Emerged in 2001, PROTACs offer an attractive therapeutic concept to control target protein levels and have made rapid progress in the drug discovery pipelines. In this GEN webinar our distinguished guest, Dr. Liping Ma, will focus on tackling the DMPK challenges of developing proteolysis-targeting chimeras by providing a research strategy for conducting in vitro ADME and in vivo PK studies, with the goal of helping drug developers quickly advance their projects.

Join this webinar to learn

  • The Developmental History of PROTACs 
  • Absorption, Distribution, Metabolism and Excretion evaluation 
  • Strength of WuXi AppTec DMPK 

Webinar presenter 

Liping Ma

WuXi AppTec 

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